Hexigel 15gm

Hexigel 15gm

(12 customer reviews)

Chlorhexidine gluconate solution I.P. equivalent to chlorhexidine gluconate 1.0% w/w in pleasantly flavoured base.

The use of Chlorhexidine gel:

The application of chlorhexidine (CHX) gel on ulcers and wound surfaces after oral surgical procedures has received considerable attention— supported scientifically by the antimicrobial properties of chlorhexidine.
Chlorhexidine acts against bacteria (Gram-positive and Gram-negative), with bacteriostatic action at low concentrations and bactericidal action at high concentrations Chlorhexidine is also known for its antiviral and antifungal effects.

Mode of action:

Chlorhexidine acts on the target micro-organisms by increasing their cell membrane permeability which causes the precipitation of cytoplasmic macromolecules and subsequent microbial death via cell lysis. Therefore, the effect of CHX is mainly based on minimizing the microbial load —playing an anti-infection role, which seems critical in the early stages of wound healing.


1. Periodontal diseases: gingivitis, periodontitis
2. Oral candidiasis, esp denture stomatitis
3. Aphthous and other oral ulcers, such as due to dentures
4. Common oral injuries, including those from orthodontic appliances and oral surgery appliances
5. Maintenance of oral hygiene, especially interdentally — in cancer patients, gingivitis & periodontitis patients, between and around restorations

Scientific basis in various clinical applications:

A. Hexigel in the prevention of alveolar osteitis (dry socket)

The extraction of third molars is a common dental procedure. The American Association of Oral and Maxillofacial Surgeons states that “about 85% of third molars will eventually need to be removed”.
Available data also shows that 5 to 30% third molar extractions can create a”dry socket” – a complication associated with severe pain.
How can we prevent this unwanted complication?
1. A meta-analysis published in “Oral Diseases” in August 2016, reviewed 11 trials and found that 0.2% chlorhexidine gel was effective in preventing alveolar osteitis after lower third molar extraction(s).
2. Journal of Oral & Maxillofacial Surgery in May 2017, reviewed Twenty-three studies published from 1979 to 2015 and concluded that chlorhexidine, used in any formulation and concentration can prevent dry socket in patients who have undergone third molar extraction. https://www.joms.org/article/S0278-2391(17)30020-4/fulltext
3. Another systematic review & meta-analysis published in May 2017 found that Chlorhexidine gel is superior to placebo in reducing the incidence of alveolar osteitis after mandibular third molar extraction.
4. The largest network meta-analysis done till now reviewed 37 randomized controlled trials that included 6175 mandibular third molar surgeries in 4716 patients. This study published in Sept 2020 showed that 0.2% Chlorhexidine gel placed in the socket can prevent dry socket after mandibular third molar surgery.
Hexigel, a 1% Chlorhexidine gluconate-based gel, is an inexpensive and easily available local application for all the 3rd molar extraction patients. They can apply it multiple times a day from the day of tooth extraction. A single tube of Hexigel contains enough quantity of gel to give protective coverage during the critical phase of the first couple of days.

Use Hexigel after every case of lower molar extraction, especially the surgical extraction of the lower wisdom tooth, and minimize the risk of dry socket.

B. Hexigel as a post-surgical gel

High-quality articles demonstrate the evidence that Chlorhexidine gel application
exerts a beneficial effect on oral surgical wound healing. Chlorhexidine gel
application significantly decreases the risk of surgical complications and/or poor
wound healing.

C. Hexigel in denture stomatitis

Denture stomatitis (DS) seen in about 15-70% of denture wearers is a condition characterized by a generalized inflammation of the denture-covered palatal mucosa. The clinical signs can vary from petechiae to generalized inflammation with papillary hyperplasia.

It is a harmless form of oral candidiasis associated with a quantitative increase of yeasts (a mixture of Candida species eg. C. albicans, C. tropicalis, C. krusei, C. guilliermondii, C. glabrata) on the mucosa and the denture’s fit surface. Complete and removable dentures accumulate, among all, C. albicans on the porous surface of the acrylic resin.

Denture hygiene is an important factor in the prevention and treatment of DS. Chlorhexidine digluconate, an effective antimicrobial agent active against various bacteria, viruses, and fungi including C. albicans, is recommended in the treatment of denture stomatitis because of its proven clinical and microbiological efficacy.

D. Hexigel in cancer patients

Patients can use an interdental brush dipped in chlorhexidine gel to clean the areas between teeth, crowns, and bridges to ensure good oral health.

E. Hexigel in periodontitis patients

Cleaning the interdental areas is a critical component of oral care in periodontitis patients.

F. Hexigel in restorative dentistry

Restorations with overhangs and rough edges can create plaque-retentive areas around the crowns, bridges, and fillings. Cleaning the interdental areas is critical to maintaining soft tissue health interdentally. Cleaning the interdental areas is a critical component of oral care in periodontitis patients.

Directions for use:

For oral hygiene, plaque inhibition and gingivitis: Brush your teeth with the gel once or twice a day. Use an interdental brush for carrying hexigel between teeth, crowns, bridges, and implants. For management of aphthous and other oral ulcers: Apply the gel to affected areas once or twice a day.


Brown staining may be reported with extensive use in some cases. It can be removed by brushing or polishing.


Lamitube of 15g (0.52 oz)

Read More
Order online

Only for Doctors


12 reviews for Hexigel 15gm

  1. MJSastry

    Excelent medicine it cure immediately the mouth ulcer

  2. Ankit Aggarwal

    Its a good gel to cure Mouth healing Problems

  3. Jamal uddin

    Very effective

  4. Trupti

    Excellent gel for curing mouth ulcer…

  5. Snehal Ambhore

    Really it is very useful for ulcers and gingivitis, but also I am interested in its effects in periodontitis when used as local drug delivery.

  6. Snehal Ambhore

    It is very useful for ulcers and gingivitis, but also I am interested in its effects in periodontitis when used as local drug delivery.

  7. Renu Pathak

    Really it is very effective

  8. Renu Pathak

    Really it is very effective

  9. Syed Zia

    very nice medicine pain remove in a second.

  10. Abhishek

    It’s working fast

  11. Rishi Bhan Singh

    Much Effective. Cures Very Fast.

  12. Deshraj

    Very effective

Add a review

Your email address will not be published. Required fields are marked *

WordPress PopUp Plugin
Quick Enquiry
close slider