Geriatric Mucosal Lesions: A Wake-Up Call from Tertiary Care Data

Dental clinicians often associate the geriatric appointment with complex restorative needs root caries, abfraction, and loose dentures. However, a 2025 retrospective study by Sharma et al. serves as a stark reminder that in high-risk populations, the most critical pathology is often on the mucosa.

The study analyzed 354 elderly patients (aged ≥60) presenting to a tertiary dental hospital in India. The headline statistic is sobering: 54.7% of these patients presented with at least one oral mucosal lesion (OML).

While this prevalence is skewed by the hospital setting (where patients are often referred because of symptoms), the distribution of these lesions offers a critical roadmap for what clinicians must look for during examinations.

The “PMD” Burden (Potentially Malignant Disorders)

The study identified a massive burden of premalignant and malignant conditions. When you combine the top findings, the risk profile becomes clear:

1. Leukoplakia (19.5%): The most common finding. This high prevalence is a “geographic fingerprint” of the cohort, likely driven by smokeless tobacco (betel quid) habits specific to the region.

2. Lichen Planus (17.8%): A close second.

3. Malignancy (13.0%):

  • Context Note: While 13% is extraordinarily high due to referral bias (tertiary oral surgery center), the combined load of Leukoplakia + Lichen Planus + Malignancy means that over 50% of diagnosed lesions in this group were either cancerous or had malignant potential.

Clinical Nuances: Reading Between the Statistics

1. The “Hidden” Denture Stomatitis Rate

Denture Stomatitis was found in only 9.0% of the total sample.

  • The Clinical Reality: This number is deceptive. Since it is calculated against the total population (not just denture wearers), the actual prevalence among patients with prostheses is likely much higher. It remains a key differential, even if overshadowed by malignancy in this specific dataset.

2. Habits Over Health History

The study found a strong, statistically significant association between Tobacco Use and Denture Wearing with lesions. Interestingly, there was no significant association with systemic diseases (diabetes/hypertension) or gender.

  • The Clinical Reality: In this cohort, pathology didn’t discriminate between men and women, likely due to shared cultural tobacco habits. Furthermore, local irritants (tobacco, friction) were the dominant drivers of disease, overpowering systemic factors. Do not rule out a lesion just because a patient’s medical history is “clean.”

3. The “Survival Bias” in Octogenarians

The researchers observed that lesion prevalence actually declined in patients over 80 years old.

  • The Clinical Reality: This is a grim example of survival bias. Patients with high-risk habits and severe lesions (malignancy) often do not survive into their 80s. The “super-elderly” patients you treat likely represent a unique “survivor cohort,” but vigilance is still required.

The Bottom Line for Practice

Geriatric dentistry is more than maintaining function; it is about active surveillance. With a high prevalence of Potentially Malignant Disorders (PMDs) in the elderly, the soft tissue exam is a high-yield diagnostic procedure. The data confirms that tobacco cessation and denture hygiene are the two most impactful preventive conversations you can have with your elderly patients before a “patch” becomes a “problem.”

Reference:

Sharma K, Chaturvedi M, Dubey R, Choudary NS, Bajana P, Voulligonda D, Tiwari HD. Prevalence of oral mucosal lesions among elderly Indian patients: A retrospective study. Bioinformation. 2025 Sep 30;21(9):3401-3403. PMID: 41466643; PMCID: PMC12744486.

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