xicaine

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  Xicaine Vials (Pack of 20..

  Composition:

  Lignocaine Hydrochloride I.P. 2% Adrenaline I.P. 1:80,000

  Mode of Action:

  Local anesthetics reversibly block nerve transmission, when applied to a limited area of the body. They bind to the sodium channels in the nerve membrane and prevent the entry of sodium ions in response to the membrane’s depolarization. A vasoconstrictor like Adrenaline added to a local anesthetic may significantly prolong the anesthetic’s duration of action by reducing the blood flow around the injection site. This in turn may reduce the local anaesthetic’s peak plasma concentration and the risk of adverse systemic reactions.

  Indications:

  Local anesthesia by infiltration or nerve block injection.

  Contraindications:

  Xicaine is contraindicated in patients with known hypersensitivity to local anesthetic of the amide type or the presence of vasoconstrictor. Adrenaline is contraindicated in patients with arterial hypertension, coronary disease, and valvular cardiac disease.

  Dosage and administration:

  Adults: 2 ml is generally sufficient. 4 to 6 ml may be used if deemed necessary for prolonged procedures.
  Adolescents between 14 to 17 and the elderly: The usual dose is 1.8 ml. Do not exceed 3.75 ml.
  Children between 6 and 14: The usual dose is 1 to 1.5 ml. Do not exceed 2.5 ml.

  Caution:

  Do not use under 3 years of age.

  Storage:

  Store in a cool dark place.

  Presentation:

  Vial of 30 ml (1.01 fl. oz)

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